Our Platform

The molecules in biology obey the physical laws of quantum mechanics and statistical thermodynamics. 

Physics-Based Simulations

At Silicon Therapeutics, we simulate biological molecules using the laws of physics, which allows us to predict interactions, energies, and the conformational behavior of our drug discovery targets. We go beyond binding, simulating the dynamic behavior of protein-ligand interactions to reveal how conformational changes drive biological activity. We integrate biophysics, biology, and medicinal chemistry to focus our simulation efforts on the problems directly relevant to our drug discovery efforts. This approach leads to a richer understanding of the relationship between protein conformations and biological outcomes, enabling the design of drug molecules for challenging drug targets that have previously been considered “undruggable”.