Molecular Dynamics

Simulating biologically relevant timescales to predict important conformational states.

Molecular Dynamics

Biological molecules are not static. They are constantly in motion in a complex environment consisting of water, cofactors, ions, and other biological molecules. In many cases, the dynamic nature of proteins is essential for their function. At Silicon Therapeutics, we study biological molecules by solving the equations of motion for all atoms and propagating the dynamics over billions of steps. This approach allows us to predict the effect of ligand binding on protein dynamics at relevant biological timescales, enabling the design of new ligands that drive protein conformations toward desired biological activity.

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About the Project Team

Silicon Therapeutics employs an exceptional team of outstanding life scientists and computer scientists with a unifying belief that we can make better medicines faster and cheaper using computers.